Rehmannia glutinosa is one of the 50 fundamental herbs used in traditional Chinese medicine, where it has the name Sheng Di huang. It is often sold as gan di huang, gan meaning "dried."
One of the traditional uses in traditional Chinese medicine for Rehmannia glutinosa has been in the area of tinnitus and hearing loss. The plant seems to have efficacy in the scavenging of free radicals in vitro. This study however, does not report the effects of Rehmannia glutinosa in human subjects.
A number of chemical constituents including iridoids, phenethyl alcohol, glycosides, cyclopentanoid monoterpenes, and norcarotenoids, have been reported from the fresh or processed roots of R. glutinosa"
Rehmannia glutinosa, or sheng di huang, is a Chinese herb commonly used as a natural treatment for numerous health conditions. In traditional Chinese medicine, it has been used to treat general hearing loss and ringing of the ears, called tinnitis. The substance is rich in antioxidants and other constituents — including norcartenoids, glycosides, iridoids, and alcohols — which have been shown to exhibit anti-inflammatory, anti-microbial, and anti-tumor activity.
Rehmannia glutinosa has been purported as a treatment for rheumatoid arthritis, an autoimmune disease that causes joint inflammation. Its proponents claim its anti-inflammatory activity reduces this swelling, and with it, the pain associated with the disease. There have been few peer-reviewed studies showing it can reduce any symptoms of rheumatoid arthritis, however.
Chinese studies have shown rehmannia glutinosa may help treat chronic kidney inflammation, or chronic nephritis, and hives, also known as urticaria. These experiments claim to have shown the anti-inflammatory activity found in its constituents, namely its iridoids, significantly reduces the inflammation caused by these conditions. The studies were also never peer-reviewed by any journal or medical organization, however, and are not considered to be factually-accurate by many doctors.
There is sufficient evidence that rehmannia glutinosa may help treat aplastic anemia, however. This disorder is a health condition that prevents bone marrow from producing enough blood cells, causing weakness, fatigue, and shortness of breath for those that suffer from it. The herbal treatment can help reduce the duration and severity of this condition. There is also some evidence that rehmannia glutinosa can reduce the side effects caused by drugs used in chemotherapy and those used to treat the human immunodeficiency virus (HIV).
Herbalists commonly use rehmannia glutinosa with licorice as a treatment for high blood pressure, or hypertension. Herbalists believe it can safely reduce blood pressure, mitigating some of the more serious side effects of hypertension. Left untreated, that condition can lead to an aneurysm, impaired thinking, stroke, heart attack, or heart failure. Proponents also claim it can help treat health conditions related to blood loss, including spotting between menstrual periods, hemorrhoid bleeding, and the fatigue and stress associated with premenstrual syndrome (PMS). There is no verifiable scientific evidence that rehmannia glutinosa can help treat any of these conditions, however.